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My favorite reaction

By drfreddy On August 23rd, 2012 · 11 Comments


Hydrogenation using palladium on carbon and ammonium formate is my favorite reaction to perform, because:

It typically doesn’t take more than 10 minutes to get the reaction going, from weighing out the starting materials until the first promising bubbles appear. Almost any solvent is good. I prefer low-boiling alcohols; methanol or ethanol. [...]

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Goldfinger chemistry, nitromethane and cross-couplings

By drfreddy On August 12th, 2012 · 4 Comments

We were watching Goldfinger (1964) the other day. Again. You gotta love the real Bond movies. Anyways, in the opening scene, about 1 minute and 47 seconds into the movie, I was able to snap a frame with quite a lot of (medicinal) chemistry in it. The whole shot lasts for about two seconds and [...]

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