The substance is 3,4-diflurothiophene, CAS # 19259-15-5. Let there be no confusion; the compound is small, but the picture is big.
When you look in the literature, you find
A lot of computational chemistry Some who magically had it as a starting material One or two lengthy preparations and miserable atom economy
Long story […]
Yay, I did live to see it! The very reaction I requested here, a little more than a year ago. Check out this fantastico, shmantastico cross-coupling, in the latest issue of the best journal on Earth:
Org. Lett. 2012, ASAP (DOI: 10.1021/ol3029109)
Do you see what I […]
6. Michael Barclay: “What do you think about chemistry Nobel prizes going to more biologically related fields? A detriment to our subject or an example of how chemistry can cross a variety of fields?”