β-Nitrostyrenes can be used for many things. Such as making speed, meth and ectsasy. Yup, this one is for you, dear reader who came here via Google. Rougly 40 % of you search for “how to make speed” or something very similar, say my Analtyics data. So, feel most welcome, dear underground Sirs and Madams. [...]
Over the past few days, Google, Facebook, Skype, Microsoft, Twitter, yeah all the big players have come forth and stated that they have never heard of PRISM, and that the NSA certainly has no backdoors to their servers and blah blah blah.
We would like to go on record [...]
Today, the 26th of May 2013 an unnamed chemist travels across the Pond to resettle as a post-doc in the United States. I’ve been invited to join a blog shower (whatever that means), in which we, your fellow writers, celebrate your big day, hopefully with a tiny element of surprise, by posting more or less [...]
This is a follow-up to the quest posted before regarding the most straightforward, but not necessarily the most elegant, synthesis of 3,4-difluorothiophene. Bear in mind, our goal was to get a decent amount of the material as swiftly as possible; a completely new reaction type for Org. Lett. would have been nice, but [...]
I am therefore delighted to be able to do so here, and hence put a final [...]
I chuckled a bit when I saw this graphical abstract. I like bromobenzene; I have written about it before.
Disclaimer: I haven’t even read the paper, this just caught my eye while aimlessly browsing ACS Mobile, one of my favorite apps.
Anyway, I figured I’d turn [...]
P450 enzyme CYP2D6 is of importance in medicinal chemistry, pharmacology and medicine. It belongs to one of the major group of liver enzymes that metabolize drugs (and other crap) that float around your system. For several reasons, CYP2D6 is especially troublesome for scientists working with discovering new drugs.
To name one such reason, the individual [...]
Take a long good look at this reaction, recently reported in a respected journal. Have you ever seen anything like it? “Unusual formation…” — an understatement of the century, if you ask me. What the Hell is going on here? A porphyrin-ish type material spitting out a C7H5 unit (a toluene minus a handful of [...]
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I would never [...]