You have the aryl bromide. You need the corresponding aniline. Buchwald-Hartwig isn’t working.

Been there. Done that. Got the t-shirt.

What to do? Check this out! A catalytic Ullman amination. No need for stochiometric amounts of copper. Ligand and solvent free. Table 3, entry 1, for instance.

JOC 2011, Article ASAP (Available here.)

The […]

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