J. Am. Chem. Soc. 1968, 90, 5034-5036. (DOI: 10.1021/ja01020a053)
I like the close proximity of the words “Bastard” and “Sir”.
J. Org. Chem. 1979, 44, 2811-2812. (DOI: 10.1021/jo01329a053)
Org. Lett. 2008, 10, 4557-4560. (DOI: 10.1021/ol801772p)
Grad students and post-docs in the labs of the chemistry top dogs seem pretty well prepared for their internal group meetings, according to stuff you sometimes find on Google. Unfortunately, few of these amazingly jam-packed slides have real links to them, even though they are indeed online, free for all to see.
So I […]
As such, DDT is an outstanding pesticide. I have seen it in action with my own eyes. Most impressive. Its use has however been banned in many Western countries for a long time now, because nature does not know what to do with it. It is very chemically stable and very lipophilic, leading […]
I just felt like showing off a little here tonight. These are the before and after pictures:
Upon work-up, many grams of a viscous oil were obtained, contaning a mixture of diastereomers (whose exact composition I cannot go into). My God, did I struggle to get the one isomer I so highly desired out […]
As we were preparing manuscripts a while ago, I spent quite some time reading through guidelines for authors for various journals. A small paragraph in JOC‘s instructions is pure gold and quite some food for thought. For reference, the full version can be retrieved here. This is an excerpt:
Remember good old reaction #86? Our new paper about it, and a couple of analogs, is officially out today!
Tetrahedron Lett. 2011, 52, 4558-4561. (DOI: 10.1016/j.tetlet.2011.06.092).
By serendipity, we discovered that hydantoins 1 could be transformed into aziridines 3 in one step upon treatment with an excess of Red-Al.
A Brief Introduction to Organic Chemistry – FINAL EXAM
This is an example from a recent publication (Org. Lett. 2011, Article ASAP. DOI: 10.1021/ol201354k).
In short, if you mix 2-hydroxy-2-methylbutan-3-one (1) with sodium hydride in the presence or absence (sic!) of ethyl formate (2) and then perform an acid workup, you will […]
Synthetic Remarks 2011, 1, 1-2.
To address the longest-standing and most burning question in every aspect of our existence – is it under controlled conditions possible to really taste the difference between Coca Cola and Pepsi Cola? – we conducted the following experiment, in accordance with the highest standards of the scientific method.
One year, one volume. Almost all journals use this widely accepted system. Tetrahedron included. Except for this small anomaly that just presented itself before my eyes. See screenshot below. Does anybody know why Volume 50 of Tetrahedron encompasses four whole calendar years? I smell a good story behind this. I expect you to enlighten […]
On a semi-hypothetical basis, I emailed a couple of native English speaking friends to ask them what they thought the correct move would be in the following situation:
Let’s say I have discovered a new reaction. Let’s say no one else was involved. Let’s say that in my current position, I have no supervisor. […]