Remember I showed you a successful crystallization of a chiral material a while ago? Probably not. It was almost three years ago. Damn. This is the old post I am talking about.
Just wanted to tell you that I am today at liberty to show you the exact structures! Our scale-up story recently hit the press.
Org. Process Res. Dev. 2014, Article ASAP (DOI: 10.1021/op500096j)
Asymmetric synthesis is great for publishing in high-impact journals. Under circumstances process chemists often refer to as “real chemistry”, however, fanciness has little if any bearing. Cost of manufacture – that is the deal-breaker in production. This concept is largely unheard of in grad school. Maybe that should change. What do you think?
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