After work-up, LCMS, GCMS and HNMR agree: Pure desired product. Woho!
New reaction type, new mechanism (which we don’t fully understand yet), new conditions. A one-step alternative to what usually takes three or four steps, arriving at a very attractive heterocycle.
I can’t go into any details right now, but we are working on a manuscript, which will hopefully be submitted within a month. Fingers crossed!
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Frackin’ awesome! this is great, thank you for posting the pics. What type of columns are they?
upon closer inspection, do not appear to be columns. Would you please describe the reaction setup? Thank you
A poor man’s Schlenk tube 🙂 Microwave vial capped with NS14 rubber septum, argon through the needle, plain oil bath, magnetic stirring.
CONGRATS!!!!!!!!!
I bet your heterocycle has sulfur in it. Great work, by the way.
I might have some nice schlenck-tubes left at my ex-bench which no one uses since no one really appreciates them….
Poor #85. Never had a chance – those vial walls look so empty and forlorn…
interesting…waiting for your manuscript…what’s heterocycle you made and temperature???
[…] var addthis_config = {"data_track_clickback":true,"ui_language":"en"};Remember good old reaction #86? Our new paper about it, and a couple of analogs, is officially out […]